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Prostate & Urologic Cancer Center Blog

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Duke Prostate & Urologic Cancer Center Blog provides updates, organizational announcements, the latest in funding opportunities and information on upcoming conferences and symposiums. This blog also highlights inspiring patient stories and the accomplishments and achievements of faculty and staff. Subscribers are invited to submit story ideas and other news of interest. Email submissions and feedback to Jessica Hyland, Editor-In-Chief.

New Prostate Cancer Prognostic Model For Enzalutamide

Researchers at the Duke Prostate & Urologic Cancer Center, led by genitourinary oncologist Andrew Armstrong, MD, have recently developed a novel nomogram, a prognostic model that measures overall survival for men with metastatic prostate cancer who were treated with enzalutamide, according to...

The Relationship of the B7H3 Immune Checkpoint to Prostate Cancer Outcomes

Prostate cancer is known to be an immune evasive tumor, often coexisting with areas of inflammation in the primary site, but without over-expression of the traditional PD-1/PD-L1 immune checkpoint, unlike many other cancer subtypes. While certain prostate cancer subsets like microsatellite high (...

Somarelli Awarded Prostate Cancer Research Funding

A team of researchers led by Duke Cancer Institute scientist Jason Somarelli, PhD, has been awarded a Prostate Cancer Research Program (PCRP) Idea Development Award — New Investigator, totaling $350,000, by the United States Department of Defense Office of Congressionally Directed Medical Research...

Can Your Treatment Regimen Affect Your Cardiovascular Health?

Nestled in the woods of Duke Forest, you will find the Center for Living Campus at Duke University. It’s an early spring morning as Harry “Randy” Chambers arrives for his weekly exercise appointment. Once inside the building’s walls, Chambers begins to warms up with a brisk walk around the track. “...

Blurring The Racial Lines On Prostate Cancer

An increased survival benefit for African-American men with advanced prostate cancer and a stronger response to hormone therapy were the centerpieces of key racial disparity studies presented by researchers from Duke’s Prostate & Urologic Cancer Center at the 2018 American Society of Clinical...

Researchers Identify Promising New Drug Target for Lethal Prostate Cancer

Targeting a protein genome-binding process that directs expression of diverse cancerous genes could be an important new therapy approach for stopping the progression of late-stage prostate cancer, according to Duke researchers. The study , published Tuesday, May 29, 2018 in the journal Proceedings...

Tests Identify When Advanced Prostate Cancer Therapies Would Benefit

Two blood tests can predict which subset of men with advanced prostate cancer will likely not benefit from anti-androgen therapies, providing doctors and patient added clarity on treatment options, according to a study led by Duke Cancer Institute . The blood tests, dubbed “liquid biopsies”, detect...

Analysis: Survival Benefit for African-Americans with Advanced Prostate Cancer

Contrary to current perceptions, certain African-American men with advanced prostate cancer have as good a chance of survival as white men and might actually have a small advantage, according to a new analysis of more than 8,000 patients who participated in clinical trials. In a study presented...

Black Patients Show Stronger Response to Hormone Therapy for Prostate Cancer

African-American men with advanced prostate cancer might be more responsive than white men to an anti-androgen drug and steroids, according to a study led by Duke Cancer Institute researchers. While median survival was similar for both black and white participants in the study, the findings...

Smell Receptor Fuels Prostate Cancer Progression

When scientists first described the receptors responsible for our sense of smell, they naturally assumed that these chemical sensors resided exclusively in the lining of our noses. But then olfactory receptors started turning up in the strangest places -- the lungs, liver, skin, heart, testes and...

Bone Scan Software Accurately Calculates Prognosis of Advanced Prostate Cancer

A software tool to automatically calculate how extensively bones have been infiltrated by prostate cancer is both accurate and speedy, capturing key prognostic information related to survival and the development of symptoms over time. The software, called the automated bone scan index, was tested...

New Advances in Overcoming Prostate Cancer Disparities

African American men are nearly two times more likely to develop prostate cancer than white men and nearly three times more likely to die from the disease. In North Carolina, the rate of prostate cancer-related deaths among African Americans is higher than the national average. Researchers at the...

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